Deciphera Pharma Takes Another Step Closer to IPO

Health and Healthcare

Published: September 18, 2017 10:35 am

Last Updated: January 12, 2020 8:04 am

Deciphera Pharmaceuticals has registered an amended S-1 form with the U.S. Securities and Exchange Commission (SEC) for its initial public offering (IPO). The company expects to price its 6.25 million shares in the range of $15 to $17 per share, with an overallotment option for an additional 937,500 shares. At the maximum price, the whole offering is valued up to $122.79 million. The company intends to list its shares on the Nasdaq under the symbol DCPH.

The underwriters for the offering are JPMorgan, Piper Jaffray and JMP Securities.

This clinical-stage biopharmaceutical company is developing new drugs to improve the lives of cancer patients by addressing key mechanisms of drug resistance that limit the rate and durability of response of many cancer therapies. Its targeted, small molecule drug candidates, designed using the proprietary kinase switch control inhibitor platform, inhibit the activation of kinases, an important family of enzymes that, when mutated or overexpressed, are known to be directly involved in the growth and spread of many cancers.

The company has built a diverse pipeline of wholly owned, orally administered drug candidates that include three clinical-stage and two research-stage programs. Management has designed the firm’s lead drug candidate DCC-2618 to inhibit the full spectrum of mutant or amplified KIT and PDGFRα kinases that drive cancers such as gastrointestinal stromal tumors (GIST).

Deciphera is studying DCC-2618 in an ongoing Phase 1 trial in patients with advanced malignancies. The company recently presented results from this Phase 1 trial that demonstrate clinical proof-of-concept at well tolerated doses in 57 heavily pretreated patients with KIT-driven or PDGFRα-driven GIST. In this study the firm observed a disease control rate of 91% at eight weeks in 33 patients, 76% at 12 weeks in 25 patients and 57% at 24 weeks in 21 patients.

The firm intends to use the net proceeds from this offering to further fund its pipeline, as well as for working capital and general corporate purposes.

Are You Still Paying With a Debit Card?

The average American spends $17,274 on debit cards a year, and it’s a HUGE mistake. First, debit cards don’t have the same fraud protections as credit cards. Once your money is gone, it’s gone. But more importantly you can actually get something back from this spending every time you swipe.

Issuers are handing out wild bonuses right now. With some you can earn up to 5% back on every purchase. That’s like getting a 5% discount on everything you buy!

Our top pick is kind of hard to imagine. Not only does it pay up to 5% back, it also includes a $200 cash back reward in the first six months, a 0% intro APR, and…. $0 annual fee. It’s quite literally free money for any one that uses a card regularly. Click here to learn more!

Flywheel Publishing has partnered with CardRatings to provide coverage of credit card products. Flywheel Publishing and CardRatings may receive a commission from card issuers.