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Top Analyst Upgrades and Downgrades (AFL, AXP, AINV, ARMH, BIIB, CELG, CS, DELL, GMCR, INFY, LOGI, LYG, MLNX, NKTR, PDLI, PCYC, REGN, RBS, UAL, LCC, VRTX, VPHM, WFT)

These are some of the top analyst upgrades, downgrades and initiations seen so far this Tuesday. There is a larger concentration around biotech and emerging pharma this morning, but that is coincidental.

AFLAC Inc. (NYSE: AFL) cut to Neutral at Stern Agee.

American Express Co. (NYSE: AXP) cut to Underweight at J.P. Morgan.

Apollo Investment Corp. (NASDAQ: AINV) cut to Neutral at J.P. Morgan.

ARM Holdings PLC (NASDAQ: ARMH) cut to Equal Weight at Morgan Stanley.

Biogen Idec Inc. (NASDAQ: BIIB) cut to Neutral at BofA/Merrill Lynch.

Celgene Corp. (NASDAQ: CELG) raised to Buy at BofA/Merrill Lynch.

Credit Suisse Group (NYSE: CS) raised to Outperform at BNP-Paribas.

Dell Inc. (NASDAQ: DELL) cut to Neutral at boutique firm Monnes Crespi Hardt.

Green Mountain Coffee Roasters Inc. (NASDAQ: GMCR) raised to Buy with $50 target at Argus.

Infosys Ltd. (NYSE: INFY) raised to Buy at UBS.

Logitech International S.A. (NASDAQ: LOGI) cut to Underperform at Credit Suisse.

Lloyds Banking Group PLC (NYSE: LYG) raised to Neutral at J.P. Morgan.

Read also: 12 Stocks Expected to Rise 50% to 100% in 2013

Mellanox Technologies Ltd. (NASDAQ: MLNX) raised to Buy at UBS.

Nektar Therapeutics (NASDAQ: NKTR) started as Buy at Lazard.

PDL BioPharma Inc. (NASDAQ: PDLI) cut to Underperform at Credit Suisse.

Pharmacyclics Inc. (NASDAQ: PCYC) started as Outperform at Credit Suisse.

Read also: The Best Biotech Stocks for 2013

Regeneron Pharmaceuticals Inc. (NASDAQ: REGN) cut to Hold at Jefferies.

Royal Bank of Scotland Group PLC (NYSE: RBS) raised to Overweight at J.P. Morgan.

United Continental Holdings Inc. (NYSE: UAL) cut to Neutral at J.P. Morgan.

US Airways Group Inc. (NYSE: LCC) cut to Neutral at J.P. Morgan.

Vertex Pharmaceuticals Inc. (NASDAQ: VRTX) cut to Neutral at Lazard.

ViroPharma Inc. (NASDAQ: VPHM) raised to Buy at BofA/Merrill Lynch.

Weatherford International Ltd. (NYSE: WFT) maintained Underperform and named Bear of the Day at Zacks.

With shares of Apple fighting to hold $500, here is how much dead air exists in the stock if the price really starts to break under $500.

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