In what is expected to be the third-highest opening weekend box office this year, “Jurassic World” is set to debut on 4,273 U.S. screens this weekend and ring up ticket sales projected at $125 million. The fourth movie in the franchise enjoys the widest release ever for a film from Universal Studios, now part of the Comcast Corp. (NASDAQ: CMCSA) empire.

In addition to the U.S. release, the movie will also screen in 66 international markets this weekend, including China, Mexico, the United Kingdom, Australia, Germany and Russia. The international box office sales could bring worldwide weekend receipts to more than $350 million, according to Variety.

The biggest opening weekend so far in 2015 belongs to “Avengers: Age of Ultron” from Walt Disney Co.’s (NYSE: DIS) Buena Vista Studios, with a total box office of $191.3 million on its first weekend. “Furious 7,” also from Universal, rang up $147.2 million on its first weekend of release.

If “Jurassic World” meets the projected $125 million total, it will rank with “Harry Potter and the Deathly Hallows Part 1” as the 16th biggest opening ever. According to a report at Variety, the film’s production budget was $150 million.

The last movie in the franchise, “Jurassic Park III,” was released in the summer of 2001 and opened with $50.1 million in first-weekend ticket sales. Total worldwide receipts came to $368.8 million. The most successful movie in the series was the first, “Jurassic Park,” which posted worldwide ticket sales of $983.8 million. That film was released in 1993, and the sequel, “The Lost World: Jurassic Park,” was released four years later and garnered a worldwide total of $618.6 million in ticket sales. Universal Studios has released all the films in the franchise and earned $1.97 billion from the first three films.

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