Incyte

INCY Q2 2025 Earnings

Reported Jul 29, 2025 at 7:06 AM ET · SEC Source

Q2 25 EPS

$1.57

BEAT +6.48%

Est. $1.47

Q2 25 Revenue

$1.22B

BEAT +5.81%

Est. $1.15B

vs S&P Since Q2 25

+14.4%

BEATING MARKET

INCY +27.9% vs S&P +13.4%

Market Reaction

Did INCY Beat Earnings? Q2 2025 Results

Incyte delivered a convincingly strong second quarter, posting non-GAAP diluted EPS of $1.57 against a consensus estimate of $1.47, a beat of 6.48%, while total revenues of $1.22 billion cleared the $1.15 billion estimate by 5.81% and grew 16.5% year… Read more Incyte delivered a convincingly strong second quarter, posting non-GAAP diluted EPS of $1.57 against a consensus estimate of $1.47, a beat of 6.48%, while total revenues of $1.22 billion cleared the $1.15 billion estimate by 5.81% and grew 16.5% year over year. The results were powered by broad commercial momentum: Jakafi contributed $763.79 million in net product revenues, up 8% year over year, while Opzelura surged 35% to $164.50 million on robust U.S. Atopic dermatitis and vitiligo demand, and newly launched Niktimvo added $36.15 million in just its second full quarter on the market. A landmark settlement with Novartis, which secured a 50% reduction in ongoing Jakafi royalty rates beginning January 2025, provided a meaningful structural tailwind to margins going forward. Incyte raised its full-year Jakafi revenue guidance to $3.00 billion to $3.05 billion and lifted Other Oncology guidance to $500 million to $520 million, reflecting continued Niktimvo uptake and accelerating Zynyz demand following its FDA approval in squamous cell anal carcinoma.

Key Takeaways

  • Jakafi 8% paid demand growth across all indications
  • Opzelura 35% revenue growth driven by increased U.S. patient demand and refills in AD and vitiligo plus ex-U.S. launches in Italy and Spain
  • Strong Niktimvo commercial launch uptake generating $36 million in its second full quarter
  • Zynyz revenue growth driven by new SCAC approval
  • Novartis royalty dispute settlement reducing Jakafi royalty rate by 50% effective January 1, 2025, resulting in $242.2 million net benefit
  • Total royalty revenues grew 10% driven by Jakavi royalty growth
24/7 Wall St

INCY YoY Financials

Q2 2025 vs Q2 2024, source: SEC Filings

24/7 Wall St

INCY Revenue by Segment

With YoY comparisons, source: SEC Filings

Q1 25 Q1 26

“As I begin my tenure as CEO, I look forward to leading Incyte through its next phase of growth and value creation for patients, partners and shareholders. Our second quarter results reflect strong growth for Jakafi® (ruxolitinib), Opzelura® (ruxolitinib) cream and Niktimvo™ (axatilimab), positioning us well to deliver on our 2025 objectives.”

— Bill Meury, Q2 2025 Earnings Press Release