Natera

NTRA Q1 2025 Earnings

Reported May 8, 2025 at 4:15 PM ET · SEC Source

Q1 25 EPS

$-0.50

Q1 25 Revenue

$501.8M

vs S&P Since Q1 25

-4.3%

TRAILING MARKET

NTRA +23.4% vs S&P +27.7%

Market Reaction

Did NTRA Beat Earnings? Q1 2025 Results

Natera posted a convincing beat across both earnings and revenue in the first quarter of 2025, reporting a net loss of $0.50 per share against analyst expectations closer to a $0.59 loss, while revenue climbed 36.5% year-over-year to $501.83 million,… Read more Natera posted a convincing beat across both earnings and revenue in the first quarter of 2025, reporting a net loss of $0.50 per share against analyst expectations closer to a $0.59 loss, while revenue climbed 36.5% year-over-year to $501.83 million, well ahead of the roughly $460.85 million consensus. The primary engine behind that top-line strength was broad-based volume growth and average selling price improvements, with total tests processed rising 16.2% to approximately 855,100, led by a 46.1% surge in oncology testing to roughly 167,700 units. Gross margin expanded meaningfully to 63.1% from 56.7% a year ago, reflecting cost discipline and favorable cash collections on prior-period tests. Operating losses widened modestly to $79.18 million as R&D and SG&A spending accelerated to support new products and clinical trials. The company generated $44.50 million in operating cash flow and ended the quarter with approximately $991.60 million in cash and investments. Encouraged by the momentum, Natera raised its full-year 2025 revenue guidance to $1.94 billion to $2.02 billion, representing approximately 26% pro-forma growth, while maintaining gross margin guidance of 60% to 64%.

Key Takeaways

  • Total test volume growth of 16.2% YoY to approximately 855,100 tests
  • Oncology test volume growth of 46.1% YoY to approximately 167,700 tests
  • Clinical oncology units grew ~16,500 sequentially from Q4 2024, a record sequential quarter growth
  • Average selling price improvements
  • Cash collections exceeding initial revenue estimates driving true-ups
  • Continued progress in reducing cost of revenues per test
  • Strong performance across all product areas: women's health, organ health, and oncology
24/7 Wall St

NTRA YoY Financials

Q1 2025 vs Q1 2024, source: SEC Filings

24/7 Wall St

NTRA Revenue by Segment

With YoY comparisons, source: SEC Filings

Q1 25 Q4 25

“We delivered another strong quarter, with volume growth across the business, including a record growth quarter for Signatera. Our progress reflects the strength of our technology and the breadth and quality of the clinical data. With multiple high-impact datasets reading out and trials underway, we believe we're in a strong position to help millions of patients in the future.”

— Steve Chapman, Q1 2025 Earnings Press Release