The previous terms for the offering were an expected price range of $15 to $17 for a total of 6 million American depositary shares (ADS). However, Nabriva is now offering 9 million ADSes with an overallotment option for an additional 1.35 million ADSes, at an expected offering price of $10.50 per ADS. The new terms would value the offering up to $108.67 million. Each ADS represents one-tenth of a common share.
The company intends to list on the Nasdaq Global Market under the symbol NBRV. The underwriters for the offering are Leerink Partners, RBC Capital, Needham and Wedbush PacGrow.
This is a clinical stage biopharmaceutical company engaged in the research and development of novel anti-infective agents to treat serious infections, with a focus on the pleuromutilin class of antibiotics. The company is developing its lead product candidate, lefamulin, to be the first pleuromutilin antibiotic available for systemic administration in humans. Nabriva is developing both intravenous (IV) and oral formulations of lefamulin for the treatment of community-acquired bacterial pneumonia (CABP) and intends to develop lefamulin for additional indications other than pneumonia.
Nabriva has completed a phase 2 clinical trial of lefamulin for acute bacterial skin and skin structure infections (ABSSSI). Based on the clinical results of lefamulin for ABSSSI, as well as its rapid tissue distribution, including substantial penetration into lung tissue and fluids, the company is preparing to initiate two international, pivotal phase 3 clinical trials of lefamulin for the treatment of moderate to severe CABP. These will be the first clinical trials the company has conducted with lefamulin for the treatment of CABP.
The company plans to initiate the first of these trials in the fall of 2015 and the second trial in the first half of 2016. Based on the expectations regarding initiation of these trials and estimates regarding patient enrollment, top-line data available for both trials is expected in late 2017. If the results of these trials are favorable, including achievement of the primary efficacy endpoints of the trials, Nabriva expects to submit applications for marketing approval for lefamulin for the treatment of CABP in both the U.S. and Europe in 2018.
The company expects to use the net proceeds from this offering to fund the clinical development of lefamulin, repay its indebtedness, and for general corporate purposes.
Want to Retire Early? Start Here (Sponsor)
Want retirement to come a few years earlier than you’d planned? Or are you ready to retire now, but want an extra set of eyes on your finances?
Now you can speak with up to 3 financial experts in your area for FREE. By simply clicking here you can begin to match with financial professionals who can help you build your plan to retire early. And the best part? The first conversation with them is free.
Click here to match with up to 3 financial pros who would be excited to help you make financial decisions.
Have questions about retirement or personal finance? Email us at [email protected]!
By emailing your questions to 24/7 Wall St., you agree to have them published anonymously on a673b.bigscoots-temp.com.
By submitting your story, you understand and agree that we may use your story, or versions of it, in all media and platforms, including via third parties.
Thank you for reading! Have some feedback for us?
Contact the 24/7 Wall St. editorial team.
Latest from 24/7
