Biophama Firms Lexicon And Poniard In The Hurt Locker

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By Douglas A. McIntyre Updated Published
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Biophama companies are horrible investments at least 90% of the time because they are gambles on the IQs of small groups of scientists and the whims of the FDA. Poniard Pharmaceuticals (PARD) and Lexicon Pharmaceuticals (LXRX) proved the point today by each dropping 10% on heavy volume.

Lexicon Pharmaceuticals told investors how well things were going for the company on February 23. The firm bragged about its advances in treatments for type 2 diabetes, rheumatoid arthritis, and carcinoid syndrome. It was a good day for Lexicon investors. Then, today the firm said it would sell $95 million worth of stock without announcing the offering price. As might be anticipated, the shares were pounded. Lexicon trades at $1.62 today, down from a 52-week high of $3.78, so some fortunate investors have lost half of their money.

Poniard Pharmaceuticals had terrible earnings and indicated that the company should have enough money to make it until the end of this year. It is not clear what will happen then. Maybe Poniard will close. The firm works on treatments for prostate and colorectal cancer. In the fourth quarter of last year, Poniard lost $13.2 million and had no revenue. For the entire year, the loss was $46.2 million. Poniard had $46 million in cash on December 31. The company’s situation is not hopeless, but investors fled the stock pushing it down to $1.62 from a 52-week high of $9.14, so some shareholders have lost 80% of their money over the last year.

The two companies have burned investors badly enough so that it will be nearly impossible for them to recovery any market confidence.

Douglas A. McIntyre

Photo of Douglas A. McIntyre
About the Author Douglas A. McIntyre →

Douglas A. McIntyre is the co-founder, chief executive officer and editor in chief of 24/7 Wall St. and 24/7 Tempo. He has held these jobs since 2006.

McIntyre has written thousands of articles for 24/7 Wall St. He is an expert on corporate finance, the automotive industry, media companies and international finance. He has edited articles on national demographics, sports, personal income and travel.

His work has been quoted or mentioned in The New York Times, The Wall Street Journal, Los Angeles Times, The Washington Post, NBC News, Time, The New Yorker, HuffPost USA Today, Business Insider, Yahoo, AOL, MarketWatch, The Atlantic, Bloomberg, New York Post, Chicago Tribune, Forbes, The Guardian and many other major publications. McIntyre has been a guest on CNBC, the BBC and television and radio stations across the country.

A magna cum laude graduate of Harvard College, McIntyre also was president of The Harvard Advocate. Founded in 1866, the Advocate is the oldest college publication in the United States.

TheStreet.com, Comps.com and Edgar Online are some of the public companies for which McIntyre served on the board of directors. He was a Vicinity Corporation board member when the company was sold to Microsoft in 2002. He served on the audit committees of some of these companies.

McIntyre has been the CEO of FutureSource, a provider of trading terminals and news to commodities and futures traders. He was president of Switchboard, the online phone directory company. He served as chairman and CEO of On2 Technologies, the video compression company that provided video compression software for Adobe’s Flash. Google bought On2 in 2009.

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