AstraZeneca

AZN Q1 2025 Earnings

Reported Apr 29, 2025 at 12:22 PM ET

Q1 25 EPS

$2.49

Q1 25 Revenue

$13.59B

vs S&P Since Q1 25

+2.2%

BEATING MARKET

AZN +32.1% vs S&P +30.0%

Market Reaction

Did AZN Beat Earnings? Q1 2025 Results

AstraZeneca opened 2025 on firm footing, posting Q1 revenue of $13.59 billion, up 10% at constant exchange rates, while core EPS climbed 21% to $2.49, reflecting broad momentum across its two largest business segments. The headline numbers were lifte… Read more AstraZeneca opened 2025 on firm footing, posting Q1 revenue of $13.59 billion, up 10% at constant exchange rates, while core EPS climbed 21% to $2.49, reflecting broad momentum across its two largest business segments. The headline numbers were lifted in part by a notably lower core tax rate of 16%, down from 21% a year earlier, following settlements with tax authorities that reduced prior-period liabilities, though management expects the full-year rate to normalize to between 18% and 22%. Oncology remained the engine of growth, with the segment reaching $5.64 billion as Enhertu surged 34% at constant exchange rates and Imfinzi grew 16%, buoyed by expanding indications in liver, biliary tract, and lung cancers. Five positive Phase III readouts, including DESTINY-Breast09 for Enhertu in first-line HER2-positive metastatic breast cancer, added pipeline credibility to the financial results. AstraZeneca reiterated its full-year 2025 guidance for high single-digit revenue growth and low double-digit core EPS growth at constant exchange rates.

Key Takeaways

  • Double-digit revenue growth in Oncology (13% CER) and BioPharmaceuticals (12% CER)
  • Strong demand and new indication expansion across key oncology medicines
  • Farxiga growth driven by heart failure and CKD indications supported by cardiorenal guidelines
  • Rapid Enhertu adoption post-NRDL enlistment in China for HER2-positive and HER2-low breast cancer
  • Tezspire sustained demand growth in severe asthma with launch momentum across multiple markets
  • Breztri fastest-growing medicine within expanding FDC triple class for COPD
  • Ultomiris growth from patient demand and conversion from Soliris across all indications
  • Lower Core tax rate of 16% due to timing of settlements with tax authorities
  • Revenue growth across all major geographic regions
24/7 Wall St

AZN YoY Financials

Q1 2025 vs Q1 2024, source: SEC Filings

24/7 Wall St

AZN Revenue by Segment

With YoY comparisons, source: SEC Filings

Q4 24 Q1 26
24/7 Wall St

AZN Revenue by Geography

With YoY comparisons, source: SEC Filings

Q4 24 Q1 26

“Our strong growth momentum has continued into 2025 and we have now entered an unprecedented catalyst-rich period for our company.”

— Pascal Soriot, Q1 2025 Earnings Press Release