Bristol Myers Squibb

BMY Q3 2025 Earnings

Reported Oct 30, 2025 at 7:09 AM ET · SEC Source

Q3 25 EPS

$1.63

BEAT +7.56%

Est. $1.52

Q3 25 Revenue

$12.22B

BEAT +3.58%

Est. $11.80B

vs S&P Since Q3 25

+26.3%

BEATING MARKET

BMY +32.3% vs S&P +6.0%

Market Reaction

Did BMY Beat Earnings? Q3 2025 Results

Bristol-Myers Squibb posted a stronger-than-expected third quarter, with non-GAAP EPS of $1.63 beating the $1.52 consensus by 7.56% and revenue of $12.22 billion topping estimates by 3.58% on 2.8% year-over-year growth, as the company's strategic piv… Read more Bristol-Myers Squibb posted a stronger-than-expected third quarter, with non-GAAP EPS of $1.63 beating the $1.52 consensus by 7.56% and revenue of $12.22 billion topping estimates by 3.58% on 2.8% year-over-year growth, as the company's strategic pivot away from aging blockbusters continued to bear fruit. The central driver was a resurgent Growth Portfolio, which climbed 18% year-over-year to $6.86 billion and now accounts for more than half of total revenue, powered by standout performances from Eliquis at $3.75 billion, up 25%, and Breyanzi surging 60% to $359 million. That momentum more than offset a 12% decline in the Legacy Portfolio, where Revlimid fell 59% to $575 million as generic erosion deepened. Management raised full-year 2025 revenue guidance to approximately $47.50 billion to $48.00 billion and narrowed non-GAAP EPS guidance to $6.40 to $6.60, reflecting continued confidence in pipeline execution; the company also announced plans to acquire Orbital Therapeutics, adding a next-generation in vivo CAR T-cell therapy candidate targeting autoimmune diseases to its roster.

Key Takeaways

  • Growth Portfolio revenues increased 18% YoY to $6.9 billion, driven by IO portfolio, Reblozyl, Camzyos and Breyanzi
  • Eliquis U.S. sales benefited from demand growth and favorable Medicare Part D Redesign (elimination of donut hole)
  • Camzyos continued strong U.S. demand in oHCM with ~14.1K patients on commercial drug, ~1.6K added in Q3
  • Reblozyl strong demand across 1L MDS-associated anemia and increasing duration of therapy, annualizing >$2B
  • Breyanzi strong demand across all indications driven by LBCL and recently approved indications, annualizing >$1B
  • SG&A expenses decreased 10% driven by ongoing strategic productivity initiative
  • Gross margin declined to 72.9% non-GAAP from 76.0% reflecting change in product mix
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BMY YoY Financials

Q3 2025 vs Q3 2024, source: SEC Filings

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BMY Revenue by Segment

With YoY comparisons, source: SEC Filings

Q1 25 Q1 26
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BMY Revenue by Geography

With YoY comparisons, source: SEC Filings

Q1 25 Q1 26

“We delivered strong results this quarter as a result of continued execution across the business and ongoing Growth Portfolio momentum.”

— Christopher Boerner, Q3 2025 Earnings Press Release