Bristol Myers Squibb

BMY Q1 2025 Earnings

Reported Apr 24, 2025 at 7:11 AM ET · SEC Source

Q1 25 EPS

$1.80

BEAT +19.88%

Est. $1.50

Q1 25 Revenue

$11.20B

BEAT +4.62%

Est. $10.71B

vs S&P Since Q1 25

-5.8%

TRAILING MARKET

BMY +26.1% vs S&P +31.8%

Market Reaction

Did BMY Beat Earnings? Q1 2025 Results

Bristol Myers Squibb delivered a stronger-than-expected first quarter in 2025, with non-GAAP EPS of $1.80 beating the $1.50 consensus estimate by 19.88% and revenue of $11.20 billion topping expectations of $10.71 billion by 4.62%, even as total sale… Read more Bristol Myers Squibb delivered a stronger-than-expected first quarter in 2025, with non-GAAP EPS of $1.80 beating the $1.50 consensus estimate by 19.88% and revenue of $11.20 billion topping expectations of $10.71 billion by 4.62%, even as total sales declined 5.6% year over year amid accelerating generic erosion in its Legacy Portfolio. The real story was the Growth Portfolio, which matched Legacy revenues at $5.56 billion and surged 16%, powered by standout performances from Breyanzi, up 146%, Camzyos, up 89%, and Reblozyl, up 35%, collectively offsetting steep declines in Revlimid, down 44%, and Sprycel, down 53%. Non-GAAP operating margin held nearly flat at 39.0% as aggressive cost actions, including a 20% reduction in SG&A, absorbed product mix headwinds. The company's commitment to domestic investment adds broader strategic context as it simultaneously pursues $3.50 billion in savings by 2027. Looking ahead, BMS raised its full-year revenue guidance to $45.80 billion to $46.80 billion and lifted non-GAAP EPS guidance to $6.70 to $7.00, reflecting continued Growth Portfolio momentum.

Key Takeaways

  • Growth Portfolio revenues grew 16% (+18% Ex-FX), driven by Opdivo, Breyanzi, Reblozyl and Camzyos and strong early U.S. launch of Cobenfy
  • Reblozyl first-line MDS-associated anemia now accounts for majority of new patient starts
  • Breyanzi is #1 CAR T in the U.S. with continued strong demand across indications driven by LBCL
  • Camzyos U.S. demand remains strong with ~11K patients on commercial drug (~1.4K added in Q1)
  • Strategic productivity initiative driving significant reduction in non-GAAP SG&A (-20%) and R&D (-5%)
  • Legacy Portfolio declined 20% due to continued generic erosion on Revlimid, Pomalyst, Sprycel, Abraxane and U.S. Medicare Part D redesign impact on Eliquis
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BMY YoY Financials

Q1 2025 vs Q1 2024, source: SEC Filings

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BMY Revenue by Segment

With YoY comparisons, source: SEC Filings

Q1 25 Q1 26
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BMY Revenue by Geography

With YoY comparisons, source: SEC Filings

Q1 25 Q1 26

“Our strong execution in the first quarter drove continued momentum across our Growth Portfolio and meaningful progress in the pipeline. We are advancing our multi-year plan to become a more agile and efficient company, while strengthening the foundation for top-tier, long-term growth. Our strategy is clear, and our actions are accelerating the delivery of transformational medicines to patients.”

— Christopher Boerner, Q1 2025 Earnings Press Release