Here Are Wednesday’s Top Wall Street Analyst Research Calls: Abbott Laboratories, Airbnb, Biogen, Cava Group, GitLab, Halliburton, Qualcomm, Seagate, Toast, and More

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By Lee Jackson Published

Quick Read

  • The constant changing of the status regarding Iran and the Middle East has kept investors on edge, unsure which direction to proceed.

  • First-quarter earnings continue to pour in, with many of the top companies posting solid results.

  • The one crucial item in earnings results this quarter is the forward guidance, as rising energy costs and increased volatility make portfolio planning for the second quarter and beyond difficult.

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Here Are Wednesday’s Top Wall Street Analyst Research Calls: Abbott Laboratories, Airbnb, Biogen, Cava Group, GitLab, Halliburton, Qualcomm, Seagate, Toast, and More

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Pre-Market Stock Futures:

Futures are trading higher as we hit the midweek point. All major indices finished lower on Tuesday as the deadline for the ceasefire approached, amid threats to cancel talks between Iran and the United States. The President extended the ceasefire again, while keeping the blockade in place, this time indefinitely, citing the “fractured government in Iran”; his foes will likely scream TACO once again. The small-cap Russell 2000 led stocks lower, closing down 1% at 2,764, while the S&P 500, which had ripped off its largest winning streak since November of 2024, closed down 0.63% at 7,064. Both the Nasdaq and the Dow Jones Industrial Average closed down 0.59% Tuesday, with the former ending the session at 24,259 and the latter at 49,149.

Treasury Bonds:  

Yields were higher across the curve in a move we have seen since the start of the war. When equities trade lower, so do bonds. The song remains the same as rising investor concerns over inflation, hawkish sentiments surrounding Kevin Warsh’s Federal Reserve Chairman confirmation hearings, and uncertainty regarding U.S.-Iran peace talks continue to pressure sovereign and corporate U.S. debt. The 30-year long bond closed Tuesday at 4.91%, while the benchmark 10-year note was last seen at 4.30%.

Oil and Gas:

As expected, with no clear signs of progress in Iran, and while the President did extend the ceasefire, the ongoing disruption to the Middle East supply chains and production capabilities continues to add volatility. Plus, the Iranian strikes on other Middle East countries’ facilities are raising the tension level. Brent Crude closed Tuesday at $99.33, up 4.03%, while West Texas Intermediate closed at $92.13, up 2.81%. Natural gas finished the day at $2.70, up 0.30%. 

Gold:

The precious metals complex remains volatile after the huge move off the lows printed in late March, as ongoing geopolitical issues and the reset in pricing after a long, massive rally continue to grind on. Gold closed trading on Tuesday at $4,719, down 2.10%, while Silver finished the day at $76.65, down 3.85%. 

Crypto:

The Cryptocurrency markets saw a strong rally to start the day on Tuesday, with Bitcoin surging at one point above $76,000, a hefty 2.7% increase from Monday’s opening price, before reversing later in the day. Ethereum also rose by more than 2% to break above $2,300 before also reversing, as traders reacted to U.S.-Iran peace talks amid rising geopolitical tensions. At 8 AM EDT, Bitcoin was trading at $78,200, while Ethereum was trading at $2,394.  

24/7 Wall St. reviews dozens of analyst research reports daily to identify new investment ideas for both investors and traders. Some of these daily analyst calls cover stocks to buy. Other calls cover stocks to sell or avoid. Remember that no single analyst call should ever be used as a basis to buy or sell a stock. 

Here are some of the top Wall Street analyst upgrades, downgrades, and initiations seen on Wednesday, April 22, 2026.  

Upgrades:

  • Airbnb (NASDAQ: ABNB | ABNB Price Prediction) was upgraded to Overweight from Equal Weight at Wells Fargo, which raised the target price for the shares to $178 from $136.
  • Biogen (NASDAQ: BIIB) was upgraded to Buy from Neutral at UBS, which boosted the target price for the legacy biotech stock to $225 from $185.
  • DT Midstream (NYSE: DTM) was upgraded to Equal Weight from Underweight at Morgan Stanley, who raised the target price for the shares to $165 fromm $139.
  • Halliburton (NYSE: HAL) was raised to Buy from Neutral at Griffin Securities, which has a $47 price target for the oil services giant.
  • Seagate Technology Holdings (NASDAQ: STX) was upgraded to Overweight from Equal Weight at Barclays.

Downgrades:

  • Abbot Laboratories (NYSE: ABT) was downgraded to Neutral from Outperform at Daiwa, which cut the target price for the stock to $92 from $113.
  • Albemarle (NYSE: ALB) was downgraded to Neutral from Buy at Rothschild & Co Redburn, which bumped the target price to $188 from $185.
  • Calix (NASDAQ: CALX) was downgraded to Market Perform from Outperform at Northland, with a $52 target price.
  • GitLab (NASDAQ: GTLB) was cut to Neutral from Buy at Bank of America, which slashed the target price for the company to $27 from $58.
  • Prudential Financial (NYSE: PRU) was downgraded to Underweight from Equal Weight at Barclays, which lowered the target price for the shares to $91 from $110.

Initiations:

  • Affirm Holdings (NASDAQ: AFRM) was initiated with an Outperform rating at BMO Capital with a $75 target price. 
  • Cava Group (NYSE: CAVA) was started with a Buy rating at Roth Capital, with a $106 target price.
  • Qualcomm (NASDAQ: QCOM) was reinstated with an Underweight rating at Barclays, which has a $130 target price.
  • Shift4 Payments (NYSE: FOUR) was started with a Market Perform rating at BMO Capital, with a $50 target price.
  • Toast (NYSE: TOST) was initiated with an Outperform rating at BMO Capital, with a $35 target price objective.

 

 

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About the Author Lee Jackson →

Lee Jackson has covered Wall Street analysts' equity and debt research and equity strategy daily for 24/7 Wall St. since 2012. His broad and diverse career, which included a stint as the creative services director at the NBC affiliate in Austin, Texas, gives him unique insight into the financial industry and world.

Lee Jackson's journey in the financial industry spans over 30 years, with nearly two decades as an institutional equity salesperson at Bear Stearns, Lehman Brothers, and Morgan Stanley. His career was marked by his presence on the sell side during pivotal Wall Street events, from the dot.com rise and bubble to the Long Term Capital Management debacle, 9/11, and the Great Recession of 2008. This is a testament to his resilience and adaptability in the face of market volatility.

Lee Jackson’s practical financial industry experience, acquired from a career at some of the biggest banks and brokerage firms, is complemented by a lifetime of writing on various platforms. This unique combination allows him to shed light on the intricacies and workings of Wall Street in a way that only someone with deep insider experience and knowledge can. Moreover, his extensive network across Wall Street continues to provide direct access for him and 24/7 Wall St., a privilege few firms enjoy.

Since 2012, Jackson’s work for 24/7 Wall St. has been featured in Barron’s, Yahoo Finance, MarketWatch, Business Insider, TradingView, Real Money, The Street, Seeking Alpha, Benzinga, and other media outlets. He attended the prestigious Cranbrook Schools in Bloomfield Hills, Michigan, and has a degree in broadcasting from the Specs Howard School of Media Arts.

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